I am happy to share our first paper on the early diagnosis and screening of Alzheimer\u2019s disease.<\/p>\n\n\n\n
https:\/\/www.nature.com\/articles\/s44328-024-00009-8<\/a><\/p>\n\n\n\n In this study, we utilize the ultra-sensitivity of FLOWER (frequency-locked optical whispering evanescent resonator) to quantify levels of the Alzheimer\u2019s disease (AD) biomarker A\u03b242 in post-mortem cerebrospinal fluid (CSF) from control, mild cognitive impairment (MCI), and AD participants. We demonstrate FLOWER\u2019s capability to <\/a>effectively screen CSF samples for AD diagnosis. Measuring A\u03b2 levels can facilitate early AD diagnosis and support drug studies and efforts to delay dementia. FLOWER was able to distinguish healthy cognitively unimpaired participants from those with MCI and AD, marking an important advancement in early diagnosis.<\/p>\n\n\n\n We would like to thank an NIGMS R35 grant, an NIA NIH R03 grant, and the Arizona Alzheimer’s Consortium for their generous support, which made this investigation possible.<\/p>\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" I am happy to share our first paper on the early diagnosis and screening of Alzheimer\u2019s disease. https:\/\/www.nature.com\/articles\/s44328-024-00009-8 In this study, we utilize the ultra-sensitivity of FLOWER (frequency-locked optical whispering evanescent resonator) to quantify levels of the Alzheimer\u2019s disease (AD) biomarker A\u03b242 in post-mortem cerebrospinal fluid (CSF) from control, mild cognitive impairment (MCI), and AD participants. We demonstrate FLOWER\u2019s capability<\/p>\n","protected":false},"author":36,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1885","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/posts\/1885","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/users\/36"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/comments?post=1885"}],"version-history":[{"count":1,"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/posts\/1885\/revisions"}],"predecessor-version":[{"id":1886,"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/posts\/1885\/revisions\/1886"}],"wp:attachment":[{"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/media?parent=1885"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/categories?post=1885"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wp.optics.arizona.edu\/jsu\/wp-json\/wp\/v2\/tags?post=1885"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}