Bridging Computation and Experiment to Advance GPCR Drug Discovery

Accelerating GPCR drug discovery through computation and experiment integrated with direct detection of ligand binding events | npj Drug Discovery
Excited to share our latest Perspective in npj Drug Discovery.
This work highlights how FLOWER enables direct, label-free detection of ligand binding, bridging computation and experiment.
Beyond conventional screening, FLOWER opens new opportunities to advance biological discovery by directly revealing molecular interactions and mechanisms that are often inaccessible with existing approaches.
Grateful to our collaborators and to the support from the National Institutes of Health that makes this work possible